Abstract
Objectives: The goal of this research was to evaluate the effects of Platelet Rich Fibrin (PRF) in reducing post-surgical complications as pain, swelling, and trismus after surgical extraction of impacted lower third molars. Methods: A total of 44 patients who fulfilled the inclusion criteria were chosen to take part in this research. Postoperative pain was assessed using a numerical rating scale (NRS). Facial swelling was measured by a modification of tape measure method. To assess trismus, the maximal interincisal mouth opening was measured by using a digital caliper scale (electronic vernier). Results: In the Platelet Rich Fibrin PRF group; the results showed a significant difference of levels of pain experienced (NRS) in the 1st postoperative day in comparison to the control group. In regard to post-operative swelling; a significant decrease in the 3rd postoperative day was observed in comparison to the control group. With regard to trismus; no significant differences between groups regarding interincisal mouth opening was noticed. Conclusions: The application of PRF reduces the severity of the immediate postoperative sequelaes.