Abstract
Aim: To evaluate the response of intraoral soft tissue by low level laser light, histologically and bio-chemically. Materials and methods: The study was performed on (20) healthy rats. A clean two sided mucoperiosteal flap was raised opposite to the area of lower incisors. The rats were divided into two groups, ten for each. Histological specimens were taken at days 5th,9thand 11th postoperative period .The dose of laser therapy in each session was 0.75 J/cm2. Each rat in each group received this dose daily for 11thdays at an interval of 15 minutes. Histopathological analysis were made for both groups detecting number of blood vessels (neovascularization),collagen arrangements and number of fibrob-lasts. Biochemical analysis of C-reactive protein(CRP) was also conducted. Results: Laser therapy showed enhancement of neovasculazation at days 5and 9 postoperatively .While collagen arrangement showed significant changes at the 5th ,9th and 11th postoperative days. Biochemical analysis showed significant increase of CRP at the 5th postoperative day. This increase was followed by a significant decrease at the 7th postoperative day in comparison with the control group. Conclusion: The present results indicated that low level laser therapy at a dose of 0.75 J/cm2 enhanced wound healing .
